Areas of Scientific Interest
Medical genetics, translational omics, effect (protective/pathogenic) alleles, personalised/individualised medicine
Main Activities / Research Directions
Our vision is a laboratory that applies innovative technologies and testing strategies to the human genome and regulome, and aims to apply this knowledge gained to the approaches of the personalised medicine.
The mission is to study and analyse the structure and regulatory mechanisms of the human genome in order to understand the interactions between genomic variation, gene expression, environmental influences and the implications for human health.
The objectives are to advance scientific knowledge in the fields of human genomics and regulomics, to foster international collaboration, and seek to apply the knowledge gained in personalised medicine.
Research
Adaptive genetic mechanisms – a comprehensive study of whole genome variation in the group of the Lithuanian Chornobyl catastrophe liquidators (ADAPT)
Analysis of biomarkers of suicidal tendencies and depression and validation of a prognostic model in Lithuania (BIOZYMUO)
Fetal Single Cell Transcriptomics (FETOME)
Genome of Lithuania (gLT)
Availability of long fragment next generation sequencing for rare disease patients (ERDERA)
Methods and Infrastructure Used
Infrastructure of the Translational Health Research Institute and Biomedical Research Institute, partner institutions
Projects
Fundamental research of human genome architecture: characterization of phenome, genome and regulome of the Lithuanian population (1.2) 150000-TP-7-7; 2019)
Cooperation
Vilnius University Hospital Santaros Klinikos
Life Sciences Center, Vilnius University
Tartu University
University of Lausanne
Aachen University Hospital
University of ULSAN
University College London (UCL)
List of Employees and Contacts
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Academic degree |
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Prof. Dr. |
Laima Ambrozaitytė (Head of Laboratory) |
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Dr. |
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Assoc. Prof. Dr. |
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Information for Those Interested in Cooperation
Cooperation and Services: the human genome and regulome factors in the context of candidate targets for personalized medicine.
Keywords: Effect (protective/pathogenic) alleles; personalized/individual medicine; single-cell genomics/transcriptomics.
For cooperation and partnerships at the Translational Health Research Institute, please contact: